Exonuclease editor promotes precision of gene editing in mammalian cells
Abstract Background Many efforts have been made to improve the precision of Cas9-mediated gene editing through increasing knock-in efficiency and decreasing byproducts, which proved to be challenging. Results Here, we have developed a human exonuclease 1-based genome-editing tool, referred to as exo...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2024-05-01
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| coleção: | BMC Biology |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12915-024-01918-w |
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