Expression Profile of Genes Related to the Th17 Pathway in Macrophages Infected by Leishmania major and Leishmania amazonensis: The Use of Gene Regulatory Networks in Modeling This Pathway

Leishmania amazonensis and Leishmania major are the causative agents of cutaneous and mucocutaneous diseases. The infections‘ outcome depends on host–parasite interactions and Th1/Th2 response, and in cutaneous form, regulation of Th17 cytokines has been reported to maintain inflammation in lesions....

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Auteurs principaux:	Leilane Oliveira Gonçalves, Andrés F. Vallejo Pulido, Fernando Augusto Siqueira Mathias, Alexandre Estevão Silvério Enes, Maria Gabriela Reis Carvalho, Daniela de Melo Resende, Marta E. Polak, Jeronimo C. Ruiz
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2022-06-01
Collection:	Frontiers in Cellular and Infection Microbiology
Sujets:	Leishmania–macrophage interaction gene regulatory network (GRN) expression profiling Th17 immune modulation
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.826523/full
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