Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.

Human breast cancer susceptibility gene, BRCA2, encodes a 3418-amino acid protein that is essential for maintaining genomic integrity. Among the proteins that physically interact with BRCA2, Partner and Localizer of BRCA2 (PALB2), which binds to the N-terminal region of BRCA2, is vital for its funct...

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Autors principals:	Suzanne A Hartford, Rajanikant Chittela, Xia Ding, Aradhana Vyas, Betty Martin, Sandra Burkett, Diana C Haines, Eileen Southon, Lino Tessarollo, Shyam K Sharan
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2016-08-01
Col·lecció:	PLoS Genetics
Accés en línia:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006236&type=printable
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