Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.
Human breast cancer susceptibility gene, BRCA2, encodes a 3418-amino acid protein that is essential for maintaining genomic integrity. Among the proteins that physically interact with BRCA2, Partner and Localizer of BRCA2 (PALB2), which binds to the N-terminal region of BRCA2, is vital for its funct...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2016-08-01
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| Serie: | PLoS Genetics |
| Accesso online: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006236&type=printable |
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