Improving the performance of polymerase chain reaction for microsatellite instability testing in endometrial cancer

Abstract Between 20% and 30% of endometrial cancer (EC) cases show mismatch repair deficiency (dMMR), and its characterisation is recommended in these tumours for molecular classification, screening of Lynch syndrome, and as a predictive biomarker for immunotherapy. The aim of this study was to expl...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Marta Mendiola, Victoria Heredia-Soto, Amparo Baillo, Ignacio Ruz-Caracuel, Rocio Mena, Alberto Berjón, Francisco Javier Escudero, Jorge Pedregosa, Alicia Hernandez, Jaime Feliu, David Hardisson, Andres Redondo
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-12-01
Serija:	Scientific Reports
Teme:	Endometrial carcinoma Mismatch repair deficiency Microsatellite instability Polymerase chain reaction OncoMate Long mononucleotide repeats
Online dostop:	https://doi.org/10.1038/s41598-025-27895-w
Oznake:	Označite Brez oznak, prvi označite!