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New thiazole, thiophene and 2-pyridone compounds incorporating dimethylaniline moiety: synthesis, cytotoxicity, ADME and molecular docking studies

Abstract Various sets of thiazole, thiophene, and 2-pyridone ring structures containing a dimethylaniline component were synthesized. Substituted thiazoles 2–3 and thiophenes 5–7 were produced by reacting thiocarbamoyl compound 4 with α-halogenated reagents in different basic conditions. Also, a ser...

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Autors principals: Heba M. Metwally, Norhan M. Younis, Ehab Abdel-Latif, Ali El-Rayyes
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-03-01
Col·lecció:BMC Chemistry
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Accés en línia:https://doi.org/10.1186/s13065-024-01136-z
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