New thiazole, thiophene and 2-pyridone compounds incorporating dimethylaniline moiety: synthesis, cytotoxicity, ADME and molecular docking studies

Abstract Various sets of thiazole, thiophene, and 2-pyridone ring structures containing a dimethylaniline component were synthesized. Substituted thiazoles 2–3 and thiophenes 5–7 were produced by reacting thiocarbamoyl compound 4 with α-halogenated reagents in different basic conditions. Also, a ser...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Heba M. Metwally, Norhan M. Younis, Ehab Abdel-Latif, Ali El-Rayyes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-03-01
Colecção:	BMC Chemistry
Assuntos:	Thiazole Thiophene 2-pyridone Anticancer MTT-assay ADME
Acesso em linha:	https://doi.org/10.1186/s13065-024-01136-z
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!