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Revisiting characteristics of oncogenic extrachromosomal DNA as mobile enhancers on neuroblastoma and glioma cancers

Abstract Cancer can be induced by a variety of possible causes, including tumor suppressor gene failure and proto-oncogene hyperactivation. Tumor-associated extrachromosomal circular DNA has been proposed to endanger human health and speed up the progression of cancer. The amplification of ecDNA has...

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Principais autores: Mohsen Karami Fath, Nastaran Karimfar, Andarz Fazlollahpour Naghibi, Shahriyar Shafa, Melika Ghasemi Shiran, Mehran Ataei, Hossein Dehghanzadeh, Mohsen Nabi Afjadi, Tahereh Ghadiri, Zahra Payandeh, Vahideh Tarhriz
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-05-01
Serier:Cancer Cell International
Fag:
Cancer
Extrachromosomal circular DNA
Drug resistance
Oncogene
Amplification
Online adgang:https://doi.org/10.1186/s12935-022-02617-8
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