Small-Molecule Host-Defense Peptide Mimetic Antibacterial and Antifungal Agents Activate Human and Mouse Mast Cells via Mas-Related GPCRs

Host-defense peptides (HDPs) have an important therapeutic potential against microbial infections but their metabolic instability and cellular cytotoxicity have limited their utility. To overcome these limitations, we utilized five small-molecule, nonpeptide HDP mimetics (smHDPMs) and tested their e...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Ibrahim Alkanfari, Katie B. Freeman, Saptarshi Roy, Tahsin Jahan, Richard W. Scott, Hydar Ali
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2019-04-01
Sarja:	Cells
Aiheet:	host-defense peptide mimetics mast cells MRGPRX2 Mrgprb2
Linkit:	https://www.mdpi.com/2073-4409/8/4/311
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!