Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis

Abstract Tumour associated neutrophils (TANs) promote metastasis through interactions of Neutrophil Extracellular Traps (NETs) with tumour cells. However, molecular details surrounding the interactions between NETs and Pancreatic Ductal Adenocarcinoma (PDAC) cells are poorly understood. Here, we exa...

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Bibliografiske detaljer

Principais autores:	Paul C. McDonald, James T. Topham, Shannon Awrey, Hossein Tavakoli, Rebekah Carroll, Wells S. Brown, Zachary J. Gerbec, Steve E. Kalloger, Joanna M. Karasinska, Patricia Tang, Rachel Goodwin, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Gregg B. Morin, Daniel J. Renouf, David F. Schaeffer, Shoukat Dedhar
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-07-01
Serier:	Communications Biology
Online adgang:	https://doi.org/10.1038/s42003-025-08440-x
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