Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis

Abstract Tumour associated neutrophils (TANs) promote metastasis through interactions of Neutrophil Extracellular Traps (NETs) with tumour cells. However, molecular details surrounding the interactions between NETs and Pancreatic Ductal Adenocarcinoma (PDAC) cells are poorly understood. Here, we exa...

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Egile Nagusiak:	Paul C. McDonald, James T. Topham, Shannon Awrey, Hossein Tavakoli, Rebekah Carroll, Wells S. Brown, Zachary J. Gerbec, Steve E. Kalloger, Joanna M. Karasinska, Patricia Tang, Rachel Goodwin, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Gregg B. Morin, Daniel J. Renouf, David F. Schaeffer, Shoukat Dedhar
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2025-07-01
Saila:	Communications Biology
Sarrera elektronikoa:	https://doi.org/10.1038/s42003-025-08440-x
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