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Insulin receptor endocytosis in the pathophysiology of insulin resistance

Insulin: Keeping the receptors signaling A potential cancer treatment also shows promise for treatment of type 2 diabetes. When insulin receptors (IRs) on cell surfaces bind to insulin, they send out signals that trigger glucose uptake, lowering blood sugar. The duration of IR signaling is crucial f...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Catherine Hall, Hongtao Yu, Eunhee Choi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2020-06-01
Schriftenreihe:Experimental and Molecular Medicine
Online-Zugang:https://doi.org/10.1038/s12276-020-0456-3
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