TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo

Premature ovarian insufficiency (POI) is a clinical syndrome of ovarian dysfunction characterized by the abnormal alteration of hormone levels such as FSH and E₂. POI causes infertility, severe daily life disturbances, and long-term health risks. However, the underlying mechanism remains...

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Bibliografiske detaljer

Principais autores:	Chong Zhou, Dandan Li, Jinxia He, Tao Luo, Yiting Liu, Yue Xue, Jian Huang, Liping Zheng, Jia Li
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2024-03-01
Serier:	Antioxidants
Fag:	premature ovarian insufficiency granulosa cells cellular senescence oxidative stress autophagy TRIM28
Online adgang:	https://www.mdpi.com/2076-3921/13/3/308
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