TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo

Premature ovarian insufficiency (POI) is a clinical syndrome of ovarian dysfunction characterized by the abnormal alteration of hormone levels such as FSH and E₂. POI causes infertility, severe daily life disturbances, and long-term health risks. However, the underlying mechanism remains...

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Autors principals:	Chong Zhou, Dandan Li, Jinxia He, Tao Luo, Yiting Liu, Yue Xue, Jian Huang, Liping Zheng, Jia Li
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-03-01
Col·lecció:	Antioxidants
Matèries:	premature ovarian insufficiency granulosa cells cellular senescence oxidative stress autophagy TRIM28
Accés en línia:	https://www.mdpi.com/2076-3921/13/3/308
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