Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen
Here, Depledge et al. use nanopore arrays for direct RNA sequencing to profile the HSV-1 transcriptome in productively infected cells. Sequencing of individual RNAs reveals a highly complex viral transcriptome including mRNAs encoding new viral fusion proteins derived by read-through transcription.
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2019-02-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-019-08734-9 |
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