RETRACTED ARTICLE: Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy

Abstract Multiple system atrophy (MSA) is a fatal neurodegenerative disorder characterized by the pathological accumulation of alpha-synuclein (α-syn) in oligodendrocytes. Therapeutic efforts to stop or delay the progression of MSA have yielded suboptimal results in clinical trials, and there are no...

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Principais autores:	Elvira Valera, Brian Spencer, Jerel A. Fields, Ivy Trinh, Anthony Adame, Michael Mante, Edward Rockenstein, Paula Desplats, Eliezer Masliah
格式:	Artigo
語言:	Inglês
出版:	BMC 2017-01-01
叢編:	Acta Neuropathologica Communications
主題:	Multiple system atrophy Alpha-synuclein Immunotherapy Single-chain antibody Lenalidomide Neuroinflammation
在線閱讀:	https://doi.org/10.1186/s40478-016-0409-1
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