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Impact of inflammation and Treg cell regulation on neuropathic pain in spinal cord injury: mechanisms and therapeutic prospects

Spinal cord injury is a severe neurological trauma that can frequently lead to neuropathic pain. During the initial stages following spinal cord injury, inflammation plays a critical role; however, excessive inflammation can exacerbate pain. Regulatory T cells (Treg cells) have a crucial function in...

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Uloženo v:
Hlavní autoři: Chunjia Zhang, Yan Li, Yan Yu, Zehui Li, Xin Xu, Zuliyaer Talifu, Wubo Liu, Degang Yang, Feng Gao, Song Wei, Liang Zhang, Han Gong, Run Peng, Liangjie Du, Jianjun Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-01-01
Edice:Frontiers in Immunology
Témata:
spinal cord injury
neuropathic pain
Treg cells
inflammation
cell therapy
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1334828/full
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