Antibodies to coagulase of Staphylococcus aureus crossreact to Efb and reveal different binding of shared fibrinogen binding repeats

Staphylococcus aureus pathology is caused by a plethora of virulence factors able to combat multiple host defence mechanisms. Fibrinogen (Fg), a critical component in the host coagulation cascade, plays an important role in the pathogenesis of this bacterium, as it is the target of numerous staphylo...

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Auteurs principaux:	Federico Bertoglio, Ya-Ping Ko, Sheila Thomas, Liliana Giordano, Francesca Romana Scommegna, Doris Meier, Saskia Polten, Marlies Becker, Srishtee Arora, Michael Hust, Magnus Höök, Livia Visai
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-09-01
Collection:	Frontiers in Immunology
Sujets:	Staphylococcus aureus monoclonal antibodies phage display fibrinogen-binding repeats coagulase Efb
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1221108/full
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