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Engineered polymer nanoparticles incorporating l-amino acid groups as affinity reagents for fibrinogen

Synthetic polymer hydrogel nanoparticles (NPs) were developed to function as abiotic affinity reagents for fibrinogen. These NPs were made using both temperature-sensitive N-isopropyl acrylamide (NIPAm) and l-amino acid monomers. Five kinds of l-amino acids were acryloylated to obtain functional mon...

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Principais autores: Yongyan Zhu, Ruixuan Liu, Dengyu Wu, Qianqian Yu, Kenneth J. Shea, Quanhong Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-10-01
coleção:Journal of Pharmaceutical Analysis
Assuntos:
Synthetic polymer nanoparticles
Amino-acid monomers
Arginine
Fibrinogen
Affinity reagent
Protein interaction
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2095177920310753
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