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BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control

Abstract Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving long‐term weight control. This is due, in part, to difficulties in identifying tolerable and efficacious small molecules or biologics capa...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Christopher L Axelrod, William T King, Gangarao Davuluri, Robert C Noland, Jacob Hall, Michaela Hull, Wagner S Dantas, Elizabeth RM Zunica, Stephanie J Alexopoulos, Kyle L Hoehn, Ingeborg Langohr, Krisztian Stadler, Haylee Doyle, Eva Schmidt, Stephan Nieuwoudt, Kelly Fitzgerald, Kathryn Pergola, Hisashi Fujioka, Jacob T Mey, Ciaran Fealy, Anny Mulya, Robbie Beyl, Charles L Hoppel, John P Kirwan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Springer Nature 2020-06-01
Rangatū:EMBO Molecular Medicine
Ngā marau:
AMPK
BAM15
mitochondria
obesity
type 2 diabetes
Urunga tuihono:https://doi.org/10.15252/emmm.202012088
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