HSV-1/TLR9-Mediated IFNβ and TNFα Induction Is Mal-Dependent in Macrophages

Innate immune response is a universal mechanism against invading pathogens. Toll-like receptors (TLRs), being part of a first line of defense, are responsible for detecting a variety of microorganisms. Among them TLR9, which is localized in endosomes, acts as a sensor for unmethylated CpG motifs pre...

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Главные авторы:	Joanna Zyzak, Małgorzata Mitkiewicz, Ewa Leszczyńska, Patryk Reniewicz, Paul N. Moynagh, Jakub Siednienko
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Karger Publishers 2019-12-01
Серии:	Journal of Innate Immunity
Предметы:	toll-like receptor 9 mal/tirap hsv-1 ifnβ nf-κb
Online-ссылка:	https://www.karger.com/Article/FullText/504542
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