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Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation

Women have higher prevalence of asthma compared with men. In asthma, allergic airway inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and IL-13 production and eosinophil infiltration. Foxp3+ Tregs suppress and ST2+ Tregs promote allergic airway inflammation....

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מידע ביבליוגרפי
Principais autores: Vivek D. Gandhi, Jacqueline-Yvonne Cephus, Allison E. Norlander, Nowrin U. Chowdhury, Jian Zhang, Zachary J. Ceneviva, Elie Tannous, Vasiliy V. Polosukhin, Nathan D. Putz, Nancy Wickersham, Amrit Singh, Lorraine B. Ware, Julie A. Bastarache, Ciara M. Shaver, Hong Wei Chu, R. Stokes Peebles Jr., Dawn C. Newcomb
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2022-02-01
סדרה:The Journal of Clinical Investigation
נושאים:
גישה מקוונת:https://doi.org/10.1172/JCI153397
תגים: הוספת תג
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