Androgen receptor signaling promotes Treg suppressive function during allergic airway inflammation
Women have higher prevalence of asthma compared with men. In asthma, allergic airway inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and IL-13 production and eosinophil infiltration. Foxp3+ Tregs suppress and ST2+ Tregs promote allergic airway inflammation....
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| Principais autores: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2022-02-01
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| coleção: | The Journal of Clinical Investigation |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1172/JCI153397 |
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