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MicroRNA-210 Enhances Cell Survival and Paracrine Potential for Cardiac Cell Therapy While Targeting Mitophagy

The therapeutic potential of presumed cardiac progenitor cells (CPCs) in heart regeneration has garnered significant interest, yet clinical trials have revealed limited efficacy due to challenges in cell survival, retention, and expansion. Priming CPCs to survive the hostile hypoxic environment may...

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Principais autores: Rita Alonaizan, Ujang Purnama, Sophia Malandraki-Miller, Mala Gunadasa-Rohling, Andrew Lewis, Nicola Smart, Carolyn Carr
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-04-01
coleção:Journal of Functional Biomaterials
Assuntos:
heart regeneration
miR-210
cell therapy
cardiac progenitor cells
myocardial infarction
hypoxia
Acesso em linha:https://www.mdpi.com/2079-4983/16/4/147
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