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MicroRNA-210 Enhances Cell Survival and Paracrine Potential for Cardiac Cell Therapy While Targeting Mitophagy

The therapeutic potential of presumed cardiac progenitor cells (CPCs) in heart regeneration has garnered significant interest, yet clinical trials have revealed limited efficacy due to challenges in cell survival, retention, and expansion. Priming CPCs to survive the hostile hypoxic environment may...

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Principais autores: Rita Alonaizan, Ujang Purnama, Sophia Malandraki-Miller, Mala Gunadasa-Rohling, Andrew Lewis, Nicola Smart, Carolyn Carr
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-04-01
Serier:Journal of Functional Biomaterials
Fag:
heart regeneration
miR-210
cell therapy
cardiac progenitor cells
myocardial infarction
hypoxia
Online adgang:https://www.mdpi.com/2079-4983/16/4/147
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