Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers

IntroductionThe management of adult relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL) remains a significant challenge, with patients presenting particularly poor historical outcomes. Novel immunotherapies, such as Blinatumomab and Inotuzumab, have revived the therapeutic landscape...

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Hlavní autoři:	Ion Antohe, Amalia Titieanu, Vlad Andrei Cianga, Cosmin Minciună, Cătălin Dănăilă, Alina Daniela Tănase, Iuliu Ivanov, Loredana Dragoş, Mihaela Zlei, Mihaela Mențel, Ciprian Tomuleasa, Anamaria Bancos, Manuela Ciocoiu, Angela Dăscălescu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-12-01
Edice:	Frontiers in Pharmacology
Témata:	B-cell acute lymphoblastic leukemia immunotherapy CAR-T cells Blinatumomab Inotuzumab
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1684382/full
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