Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells

Abstract Background Interleukin-6 (IL-6) is a multifunctional cytokine that controls the immune response, and its role has been described in the development of autoimmune diseases. Signaling via its cognate IL-6 receptor (IL-6R) complex is critical in tumor progression and, therefore, IL-6R represen...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Yaroslava Groza, Lukáš Lacina, Milan Kuchař, Leona Rašková Kafková, Kateřina Zachová, Olga Janoušková, Radim Osička, Jiří Černý, Hana Petroková, Joanna Maria Mierzwicka, Natalya Panova, Petr Kosztyu, Kristýna Sloupenská, Jan Malý, Jozef Škarda, Milan Raška, Karel Smetana, Petr Malý
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2024-05-01
سلاسل:	Cell Communication and Signaling
الموضوعات:	IL-6 IL-6R blockers Cancer cell migration Migrastatics Malignant melanoma Pancreatic carcinoma
الوصول للمادة أونلاين:	https://doi.org/10.1186/s12964-024-01630-w
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!