Alpha-ketoglutarate accelerates granulocyte-monocyte progenitor differentiation and atherosclerotic plaque inflammation via oxoglutarate receptor 1

Accumulating evidence shows that excess cholesterol and glucose uptake stimulates the expansion of hematopoietic stem/progenitor cells and myeloid progenitors, resulting in increased production of inflammatory cells and atherosclerotic progression. However, the role of other metabolites in plaque pr...

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Auteurs principaux:	Jiwei Zhao, Li Su, Wenhao Li, Sin Man Lam, Cen Yan, Taotao Zhou, Yalan Deng, Yuan Dong, Yuan Zhou, Guanghou Shui, Yingmei Feng
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2026-06-01
Collection:	Redox Biology
Sujets:	α-ketoglutarate Granulocyte-monocyte progenitor Purine nucleoside phosphorylase Myeloid cell Atherosclerosis
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2213231726001321
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