Granulocyte-Derived Extracellular Vesicles Activate Monocytes and Are Associated With Mortality in Intensive Care Unit Patients

To understand how extracellular vesicle (EV) subtypes differentially activate monocytes, a series of in vitro studies were performed. We found that plasma-EVs biased monocytes toward an M1 profile. Culturing monocytes with granulocyte-, monocyte-, and endothelial-EVs induced several pro-inflammatory...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Ali Danesh, Heather C. Inglis, Mohamed Abdel-Mohsen, Xutao Deng, Avril Adelman, Kenneth B. Schechtman, John W. Heitman, Ryan Vilardi, Avani Shah, Sheila M. Keating, Mitchell J. Cohen, Evan S. Jacobs, Satish K. Pillai, Jacques Lacroix, Philip C. Spinella, Philip J. Norris
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2018-05-01
श्रृंखला:	Frontiers in Immunology
विषय:	extracellular vesicles monocytes granulocytes exosomes microvesicles mortality
ऑनलाइन पहुंच:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00956/full
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