The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants
Abstract We investigate the mechanism associated with the severity of COVID-19 in men with TLR7 mutation. Men with loss-of-function (LOF) mutations in TLR7 had severe COVID-19. LOF mutations in TLR7 increased the risk of critical COVID by 16.00-fold (95% confidence interval 2.40–106.73). The deleter...
שמור ב:
| Principais autores: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Portfolio
2023-08-01
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| סדרה: | Scientific Reports |
| גישה מקוונת: | https://doi.org/10.1038/s41598-023-40114-8 |
| תגים: |
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