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Reporter Replicons for Antiviral Drug Discovery against Positive Single-Stranded RNA Viruses

Single-stranded positive RNA ((+) ssRNA) viruses include several important human pathogens. Some members are responsible for large outbreaks, such as Zika virus, West Nile virus, SARS-CoV, and SARS-CoV-2, while others are endemic, causing an enormous global health burden. Since vaccines or specific...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Rafaela S. Fernandes, Marjorie C. L. C. Freire, Renata V. Bueno, Andre S. Godoy, Laura H. V. G. Gil, Glaucius Oliva
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-05-01
Schriftenreihe:Viruses
Schlagworte:
replicon systems
(+) ssRNA viruses
direct-acting antivirals
drug discovery
Online-Zugang:https://www.mdpi.com/1999-4915/12/6/598
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