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Dimming the corona: studying SARS-coronavirus-2 at reduced biocontainment level using replicons and virus-like particles

ABSTRACT The coronavirus-induced disease 19 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections, has had a devastating impact on millions of lives globally, with severe mortality rates and catastrophic social implications. Developing tools for effec...

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Principais autores: Grace Neilsen, Asha Maria Mathew, Jose M. Castro, William M. McFadden, Xin Wen, Yee T. Ong, Philip R. Tedbury, Shuiyun Lan, Stefan G. Sarafianos
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2024-12-01
Serier:mBio
Fag:
SARS-CoV-2
COVID-19
replicon
virus-like particles
coronavirus
drug discovery
Online adgang:https://journals.asm.org/doi/10.1128/mbio.03368-23
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