Xanthohumol modulate autophagy and ER stress to counteract stemness and enhance cisplatin efficacy in head and neck squamous cell carcinoma

Abstract Natural compounds have been increasingly investigated for their efficient anti-cancer activity. Xanthohumol (XN), a flavonoid derived from hops, has shown promise in preclinical studies for various cancers due to its unique biological properties. This study investigates the effects of XN an...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Vitale Del Vecchio, Ibone Rubio Sanchez-Pajares, Sameer Kumar Panda, Ayesha Rehman, Vincenzo De Falco, Aditya Nigam, Laura Mosca, Diana Russo, Claudia Arena, Maria Maddalena Nicoletti, Vincenzo Desiderio, Gianpaolo Papaccio, Luigi Mele, Luigi Laino
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-04-01
Цуврал:	Scientific Reports
Нөхцлүүд:	Xanthohumol HNSCC UPR Cancer stem cells Endoplasmic reticulum stress Autophagy
Онлайн хандалт:	https://doi.org/10.1038/s41598-025-98003-1
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!