Xanthohumol modulate autophagy and ER stress to counteract stemness and enhance cisplatin efficacy in head and neck squamous cell carcinoma

Abstract Natural compounds have been increasingly investigated for their efficient anti-cancer activity. Xanthohumol (XN), a flavonoid derived from hops, has shown promise in preclinical studies for various cancers due to its unique biological properties. This study investigates the effects of XN an...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Vitale Del Vecchio, Ibone Rubio Sanchez-Pajares, Sameer Kumar Panda, Ayesha Rehman, Vincenzo De Falco, Aditya Nigam, Laura Mosca, Diana Russo, Claudia Arena, Maria Maddalena Nicoletti, Vincenzo Desiderio, Gianpaolo Papaccio, Luigi Mele, Luigi Laino
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2025-04-01
Rangatū:	Scientific Reports
Ngā marau:	Xanthohumol HNSCC UPR Cancer stem cells Endoplasmic reticulum stress Autophagy
Urunga tuihono:	https://doi.org/10.1038/s41598-025-98003-1
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!