Domperidone Inhibits <i>Clostridium botulinum</i> C2 Toxin and <i>Bordetella pertussis</i> Toxin

<i>Bordetella pertussis</i> toxin (PT) and <i>Clostridium botulinum</i> C2 toxin are ADP-ribosylating toxins causing severe diseases in humans and animals. They share a common translocation mechanism requiring the cellular chaperones Hsp90 and Hsp70, cyclophilins, and FK506-binding proteins to trans...

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Autores principales:	Jinfang Jia, Maria Braune-Yan, Stefanie Lietz, Mary Wahba, Arto T. Pulliainen, Holger Barth, Katharina Ernst
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2023-06-01
Colección:	Toxins
Materias:	AB-type protein toxin ADP-ribosylating toxin pertussis toxin whooping cough C2 toxin membrane transport
Acceso en línea:	https://www.mdpi.com/2072-6651/15/7/412
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