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Deciphering the role of SAMHD1 in endometrial cancer progression

Abstract Background Endometrial cancer (EC) presents significant clinical challenges due to its heterogeneity and complex pathophysiology. SAMHD1, known for its role as a deoxynucleotide triphosphate triphosphohydrolase, has been implicated in the progression of various cancers, including EC. This s...

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Principais autores: Ping Qiang, Ying Chen, Yang Shao, Qicheng Deng, Songyuan Xu, Weipei Zhu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-10-01
Serier:Biology Direct
Fag:
dNTP hydrolysis enzyme
SAMHD1
TRIM27
Ubiquitination
PTEN
PI3K/AKT signaling pathway
Online adgang:https://doi.org/10.1186/s13062-024-00525-7
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