Design of the MERCURION-IPF trial – intravenous immunoglobulin for the treatment of acute exacerbations of idiopathic pulmonary fibrosis

IntroductionDespite their profound clinical impact and high mortality, acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) still lack any effective or standardized treatment strategies. This manuscript describes the rationale and design of a randomized, multicenter, open-label Phase III cl...

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Autors principals:	Vasilina Sotiropoulou, Fotios Sampsonas, Eirini Vasarmidi, Katerina Antoniou, Athena Gogali, Konstantinos Kostikas, Fotios Drakopanagiotakis, Paschalis Steiropoulos, George Margaritopoulos, Konstantinos Porpodis, Zoe Daniil, Ioannis Tomos, Ilias Papanikolaou, Vasilios Tzilas, Stelios Loukides, Argyrios Tzouvelekis
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-05-01
Col·lecció:	Frontiers in Immunology
Matèries:	acute exacerbation of idiopathic pulmonary fibrosis clinical trial idiopathic pulmonary fibrosis intravenous immunoglobulin protocol
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1777564/full
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