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Ex vivo removal of pro-fibrotic collagen and rescue of metabolic function in human ovarian fibrosis

Summary: Tissue fibrosis, with the excessive accumulation of extracellular matrix, leads to organ dysfunction. The ovary shows signs of fibrosis from an early age, creating a permissive environment for ovarian cancer. A robust culture-platform to study human ovarian fibrosis would enable screens for...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Julieta S. Del Valle, Ruben W. Van Helden, Ioannis Moustakas, Fu Wei, Joyce D. Asseler, Jeroen Metzemaekers, Gonneke S.K. Pilgram, Christine L. Mummery, Lucette A.J. van der Westerlaken, Norah M. van Mello, Susana M. Chuva de Sousa Lopes
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2025-03-01
Rangatū:iScience
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2589004225002809
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