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Multiplex Real-Time PCR Assays that Measure the Abundance of Extremely Rare Mutations Associated with Cancer.

We describe the use of "SuperSelective" primers that enable the detection and quantitation of somatic mutations whose presence relates to cancer diagnosis, prognosis, and therapy, in real-time PCR assays that can potentially analyze rare DNA fragments present in blood samples (liquid biopsies). The...

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主要な著者: Diana Y Vargas, Fred Russell Kramer, Sanjay Tyagi, Salvatore A E Marras
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2016-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC4887114?pdf=render
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