Astaxanthin mitigates cardiac toxicity induced via doxorubicin by alleviating mitochondrial fission and autophagy in rats

Abstract Doxorubicin (DOX)-induced cardiotoxicity is the most prevalent adverse reaction of DOX during chemotherapy and significantly impacts its clinical application. At present, clinical interventions for mitigating DOX-induced cardiotoxicity remain sub-optimal. Mitochondria are the primary target...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Yongjing He, Dan Wu, Qianqian Wu, Sisi Huang, Yuansheng Zhan, Jiaqiang Deng, Jing yu Chen, Lu xie, Junhui Zheng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-09-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Astaxanthin Doxorubicin Cardiotoxicity Mitochondrial dynamics Mitochondria autophagy
Online-Zugang:	https://doi.org/10.1038/s41598-025-17253-1
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!