GRK6 Depletion Induces HIF Activity in Lung Adenocarcinoma

G protein-coupled receptor kinase 6 (GRK6) is expressed in various tissues and is involved in the development of several diseases including lung cancer. We previously reported that GRK6 is down-regulated in lung adenocarcinoma patients, which induces cell invasion and metastasis. However, further un...

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Hlavní autoři:	Sumei Yao, Ayse Ertay, Yilu Zhou, Liudi Yao, Charlotte Hill, Jinliang Chen, Yangbo Guan, Hui Sun, Rob M. Ewing, Yifei Liu, Xuedong Lv, Yihua Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-05-01
Edice:	Frontiers in Oncology
Témata:	GRK6 HIF lung adenocarcinoma hypoxia EMT
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2021.654812/full
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