Stress-induced protein disaggregation in the endoplasmic reticulum catalysed by BiP
Aggregation of misfolded proteins underlie dementias. Here, the authors show that stressed cells activate an innate mechanism to resolve aggregates of defective proteins in the endoplasmic reticulum, where a third of cellular proteins are produced.
Salvato in:
| Autori principali: | , , , , , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2022-05-01
|
| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-022-30238-2 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|