Belzutifan for patients with Von Hippel-Lindau (VHL) disease-associated heterogeneous tumors – a retrospective single center analysis

Abstract Background Von Hippel-Lindau (VHL) disease is a hereditary tumor predisposition syndrome characterized by benign and malignant tumors affecting multiple organ systems. Standard treatment primarily involves surgical resection and tumor ablation, which can lead to progressive organ dysfunctio...

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Detalhes bibliográficos

Principais autores:	Kilian Rhein, Fruzsina Kotsis, Athina Ganner, Sophie Astheimer, Christine Julia Gizaw, Yannik Laich, Cordula Annette Jilg, Jan-Helge Klingler, Elke Neumann-Haefelin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-11-01
Colecção:	BMC Cancer
Assuntos:	Von Hippel-Lindau disease Belzutifan HIF-2α inhibitor Renal cell carcinoma Hemangioblastoma Neuroendocrine tumors
Acesso em linha:	https://doi.org/10.1186/s12885-025-15192-8
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