Peptide Bond Formation between Aminoacyl-Minihelices by a Scaffold Derived from the Peptidyl Transferase Center

The peptidyl transferase center (PTC) in the ribosome is composed of two symmetrically arranged tRNA-like units that contribute to peptide bond formation. We prepared units of the PTC components with putative tRNA-like structure and attempted to obtain peptide bond formation between aminoacyl-minihe...

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Bibliographic Details

Main Authors:	Mai Kawabata, Kentaro Kawashima, Hiromi Mutsuro-Aoki, Tadashi Ando, Takuya Umehara, Koji Tamura
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2022-04-01
Series:	Life
Subjects:	tRNA minihelix peptide bond formation ribosomal symmetrical region proto-ribosome
Online Access:	https://www.mdpi.com/2075-1729/12/4/573
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