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Expression Pattern of a Mini Human PrP Gene Promoter in Transgenic Mice

The prion protein is central to the pathogenesis of prion diseases, although its exact function remains unclear. Although transgenic mice have been widely utilised in prion research, their PrP expression patterns have not been characterised in detail. We have studied the developmental temporal and s...

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Bibliografiske detaljer
Principais autores: E.A. Asante, I. Gowland, J.M. Linehan, S.P. Mahal, J. Collinge
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2002-06-01
Serier:Neurobiology of Disease
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996102904869
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