Charge Transfer Complex of Lorlatinib with Chloranilic Acid: Characterization and Application to the Development of a Novel 96-Microwell Spectrophotometric Assay with High Throughput

Lorlatinib (LRL) is the first drug of the third generation of anaplastic lymphoma kinase (ALK) inhibitors used a first-line treatment of non-small cell lung cancer (NSCLC). This study describes, for the first time, the investigations for the formation of a charge transfer complex (CTC) between LRL,...

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Bibliographic Details

Main Authors:	Hany W. Darwish, Ibrahim A. Darwish, Awadh M. Ali, Halah S. Almutairi
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2023-05-01
Series:	Molecules
Subjects:	lorlatinib non-small cell lung cancer charge transfer reaction chloranilic acid microwell spectrophotometric assay high-throughput analysis
Online Access:	https://www.mdpi.com/1420-3049/28/9/3852
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