Medicarpin induces G1 arrest and mitochondria-mediated intrinsic apoptotic pathway in bladder cancer cells

Bladder cancer (BC) is the tenth most commonly diagnosed cancer. High recurrence, chemoresistance, and low response rate hinder the effective treatment of BC. Hence, a novel therapeutic strategy in the clinical management of BC is urgently needed. Medicarpin (MED), an isoflavone from Dalbergia odori...

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Hlavní autoři:	Chen Yuan, Yin Liqi, Hao Mingxuan, Xu Wenkai, Gao Jixian, Sun Yuxin, Wang Qiao, Chen Shi, Liang Youfeng, Guo Rui, Zhang Jinku, Li Jinmei, Zhai Qiongli, Cheng Runfen, Wang Jiansong, Wang Haifeng, Yang Zhao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Sciendo 2023-06-01
Edice:	Acta Pharmaceutica
Témata:	bladder cancer medicarpin cell cycle arrest apoptosis therapy
On-line přístup:	https://doi.org/10.2478/acph-2023-0016
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