PROM2 exacerbates CCl4-Induced liver fibrosis via NLRP3 inflammasome activation and hepatocyte pyroptosis
Abstract Background Liver fibrosis is a progressive disorder resulting from chronic liver injury, and its molecular mechanism remains incompletely elucidated. Methods The role of PROM2 was assessed by integrating transcriptomic datasets with in vivo liver fibrosis models. Functional analyses were pe...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer
2025-11-01
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| Col·lecció: | Cellular and Molecular Life Sciences |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1007/s00018-025-05920-5 |
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