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Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376

Porcine epidemic diarrhea virus (PEDV), being highly virulent and contagious in piglets, has caused significant damage to the pork industries of many countries worldwide. There are no commercial drugs targeting coronaviruses (CoVs), and few studies on anti-PEDV inhibitors. The coronavirus 3C-like pr...

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Principais autores: Gang Ye, Xiaowei Wang, Xiaohan Tong, Yuejun Shi, Zhen F. Fu, Guiqing Peng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-02-01
coleção:Viruses
Assuntos:
coronavirus
pedv 3cl<sup>pro</sup>
inhibitor
crystal structure
complex
Acesso em linha:https://www.mdpi.com/1999-4915/12/2/240
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