Natural Compound ZINC12899676 Reduces Porcine Epidemic Diarrhea Virus Replication by Inhibiting the Viral NTPase Activity

Porcine epidemic diarrhea virus (PEDV) is an alphacoronavirus (α-CoV) that causes high mortality in suckling piglets, leading to severe economic losses worldwide. No effective vaccine or commercial antiviral drug is readily available. Several replicative enzymes are responsible for coronavirus repli...

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Principais autores:	Pengcheng Wang, Xianwei Wang, Xing Liu, Meng Sun, Xiao Liang, Juan Bai, Ping Jiang
格式:	Artigo
语言:	Inglês
出版:	Frontiers Media S.A. 2022-05-01
丛编:	Frontiers in Pharmacology
主题:	ZINC12899676 PEDV replication virtual screening nsp13 NTPase deep learning
在线阅读:	https://www.frontiersin.org/articles/10.3389/fphar.2022.879733/full
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